1. Iran Nuclear Deal: Trump pulled out of the Obama-era nuclear agreement with Iran in 2018. Hence, a second term might mean increased tensions with Iran.
2. Palestinian-Israeli conflict: Trump recognized Jerusalem as Israel’s capital and proposed a peace plan largely favoring Israel. These actions could potentially alter the ground dynamics of the conflict.
3. Relations with Saudi Arabia: Trump showed support for Saudi Arabia despite concerns over its record on human rights. This could continue in a second term, influencing America’s reputation regarding human rights enforcement.
4. American troops: Trump has voiced a desire to bring American troops home from places like Syria, Iraq, and Afghanistan. The decisions regarding this could significantly impact stability in the region.
5. Turkey and the Kurds: Trump has been criticized for pulling forces out of northern Syria in 2019, effectively allowing Turkey to move in against the Kurdish forces. A second term might bring more changes in relations with these crucial groups.
6. Yemen War: The Trump administration has supported Saudi Arabia in the Yemen conflict. This could have significant implications for the humanitarian crisis in Yemen.
Remember, this is only an analysis based on past actions and trends, not a prediction of what would definitely happen.